A large language model, similar to the AI that powers ChatGPT, has been utilized to develop a version of a bacteria-killing drug that was once toxic to humans. In a hopeful development for the demand for safer and more effective antibiotics, researchers at The University of Texas at Austin have utilized artificial intelligence to create [...]]]> https://scitechdaily.com/ai-transforms-toxic-antibiotic-into-life-saving-medicine/feed/ 0 https://scitechdaily.com/how-safe-are-your-antibiotics-new-study-reveals-hidden-dangers/ https://scitechdaily.com/how-safe-are-your-antibiotics-new-study-reveals-hidden-dangers/#respond Thu, 08 Aug 2024 15:00:08 +0000 https://scitechdaily.com/?p=403736

A study involving elderly adults in Ontario reveals that certain oral antibiotics significantly increase the risk of severe drug rashes, leading to emergency visits and potentially fatal outcomes. Researchers advocate for the cautious prescribing of antibiotics, especially among older adults, highlighting that while most hospital visits are non-fatal, a small percentage result in intensive care [...]]]> https://scitechdaily.com/how-safe-are-your-antibiotics-new-study-reveals-hidden-dangers/feed/ 0 https://scitechdaily.com/the-predictive-power-of-gut-bacteria-in-thoroughbred-racing/ https://scitechdaily.com/the-predictive-power-of-gut-bacteria-in-thoroughbred-racing/#respond Wed, 07 Aug 2024 09:00:30 +0000 https://scitechdaily.com/?p=403583

A study from the University of Surrey shows that the gut bacteria of Thoroughbred racehorses at one month old can predict their future performance and health. By analyzing fecal samples from 52 foals, researchers found that those with higher bacterial diversity excelled in races and had fewer health issues. Additionally, the study highlights the negative [...]]]> https://scitechdaily.com/the-predictive-power-of-gut-bacteria-in-thoroughbred-racing/feed/ 0 https://scitechdaily.com/happy-accident-leads-to-potent-weapon-against-flesh-eating-superbugs/ https://scitechdaily.com/happy-accident-leads-to-potent-weapon-against-flesh-eating-superbugs/#respond Fri, 02 Aug 2024 18:00:36 +0000 https://scitechdaily.com/?p=402741

A new antibiotic compound developed by Washington University researchers effectively treats severe bacterial infections, including flesh-eating disease, in mice. The study, indicating broad-spectrum activity against drug-resistant bacteria, shows the compound also aids in quicker recovery and reduced infection severity. However, extensive testing and clinical trials are required before it reaches the market. Breakthrough in Antibiotic [...]]]> https://scitechdaily.com/happy-accident-leads-to-potent-weapon-against-flesh-eating-superbugs/feed/ 0 https://scitechdaily.com/100-million-times-more-difficult-revolutionary-dual-action-antibiotic-makes-bacterial-resistance-nearly-impossible/ https://scitechdaily.com/100-million-times-more-difficult-revolutionary-dual-action-antibiotic-makes-bacterial-resistance-nearly-impossible/#comments Mon, 29 Jul 2024 05:31:46 +0000 https://scitechdaily.com/?p=401029

A groundbreaking study from the University of Illinois Chicago unveils macrolones, a new type of antibiotic that targets bacteria in two ways, drastically reducing the potential for resistance and marking a significant step forward in infectious disease treatment. A newly discovered antibiotic, which targets two different cellular mechanisms, could make it 100 million times harder [...]]]> https://scitechdaily.com/100-million-times-more-difficult-revolutionary-dual-action-antibiotic-makes-bacterial-resistance-nearly-impossible/feed/ 2 https://scitechdaily.com/fathers-gut-microbiota-the-hidden-key-to-offspring-health/ https://scitechdaily.com/fathers-gut-microbiota-the-hidden-key-to-offspring-health/#respond Wed, 24 Jul 2024 05:20:04 +0000 https://scitechdaily.com/?p=400797

Research conducted by the Hackett group at the European Molecular Biology Laboratory (EMBL) in Rome indicates that altering the gut microbiome of male mice elevates the likelihood of disease in their subsequent generations. Research led by the Hackett group at EMBL revealed that disrupting the gut microbiota in male mice affects their offspring, resulting in [...]]]> https://scitechdaily.com/fathers-gut-microbiota-the-hidden-key-to-offspring-health/feed/ 0 https://scitechdaily.com/how-mans-best-friend-is-unlocking-the-secrets-to-beat-e-coli-superbugs/ https://scitechdaily.com/how-mans-best-friend-is-unlocking-the-secrets-to-beat-e-coli-superbugs/#respond Tue, 16 Jul 2024 13:00:10 +0000 https://scitechdaily.com/?p=399134

A new study reveals a unique genetic mutation in dogs that may contribute to antimicrobial resistance in E. coli, suggesting dogs as effective models for studying human infections. The research identifies obsolete genes in E. coli that trap antibiotics, offering new avenues for therapy and enhancing antibiotic stewardship in veterinary practices. Researchers studying antimicrobial-resistant E. [...]]]> https://scitechdaily.com/how-mans-best-friend-is-unlocking-the-secrets-to-beat-e-coli-superbugs/feed/ 0 https://scitechdaily.com/revolutionizing-antibiotics-how-mits-water-soluble-enzymes-could-change-the-game/ https://scitechdaily.com/revolutionizing-antibiotics-how-mits-water-soluble-enzymes-could-change-the-game/#comments Thu, 04 Jul 2024 07:29:05 +0000 https://scitechdaily.com/?p=394983

Scientists created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics. MIT researchers have engineered a water-soluble histidine kinase, a bacterial enzyme that could lead to a new class of antibiotics aimed at addressing the growing issue of antibiotic resistance. This development also paves [...]]]> https://scitechdaily.com/revolutionizing-antibiotics-how-mits-water-soluble-enzymes-could-change-the-game/feed/ 1 https://scitechdaily.com/probing-microbial-dark-matter-largest-ever-discovery-effort-uncovers-800000-new-antibiotic-candidates/ https://scitechdaily.com/probing-microbial-dark-matter-largest-ever-discovery-effort-uncovers-800000-new-antibiotic-candidates/#respond Fri, 28 Jun 2024 00:40:32 +0000 https://scitechdaily.com/?p=393827

Researchers at Penn Medicine analyzed genomic data to discover new antibiotics within the global microbiome. Nearly a century after the groundbreaking introduction of antibiotics such as penicillin, which transformed medicine by tapping into the natural antibacterial properties of microbes, a new study led by the Perelman School of Medicine at the University of Pennsylvania indicates [...]]]> https://scitechdaily.com/probing-microbial-dark-matter-largest-ever-discovery-effort-uncovers-800000-new-antibiotic-candidates/feed/ 0 https://scitechdaily.com/ai-transforms-sepsis-care-with-faster-more-effective-treatments/ https://scitechdaily.com/ai-transforms-sepsis-care-with-faster-more-effective-treatments/#respond Fri, 14 Jun 2024 18:00:49 +0000 https://scitechdaily.com/?p=391953

Researchers at Day Zero Diagnostics have developed Keynome gAST, an AI-driven genomic Antimicrobial Susceptibility Test that quickly predicts antimicrobial resistance by analyzing bacterial genomes from blood samples. This breakthrough, demonstrated at ASM Microbe, could drastically improve sepsis diagnosis and treatment, speeding up decision-making and potentially saving lives amidst increasing antimicrobial resistance. Sepsis is a life-threatening [...]]]> https://scitechdaily.com/ai-transforms-sepsis-care-with-faster-more-effective-treatments/feed/ 0 https://scitechdaily.com/cutting-edge-phage-research-promises-new-solutions-for-old-pathogens/ https://scitechdaily.com/cutting-edge-phage-research-promises-new-solutions-for-old-pathogens/#respond Wed, 29 May 2024 04:59:26 +0000 https://scitechdaily.com/?p=375886

New research details long-sought mechanisms and structures. Bacterial infections present major hurdles in both agriculture and healthcare, particularly with the increasing prevalence of antibiotic-resistant bacteria. Researchers at Texas A&M AgriLife Research are investigating how viruses that infect bacteria neutralize these harmful pathogens, opening the door to innovative treatment approaches. In their recent study published in [...]]]> https://scitechdaily.com/cutting-edge-phage-research-promises-new-solutions-for-old-pathogens/feed/ 0 https://scitechdaily.com/velcro-vs-bacteria-a-new-twist-in-antibiotic-warfare/ https://scitechdaily.com/velcro-vs-bacteria-a-new-twist-in-antibiotic-warfare/#respond Thu, 23 May 2024 09:00:50 +0000 https://scitechdaily.com/?p=385899

Researchers discovered a novel antibacterial mechanism of plectasin, an antibiotic derived from a fungus. The study reveals that plectasin forms Velcro-like structures that trap crucial bacterial components, preventing their escape and enhancing drug effectiveness. This mechanism could guide the development of new antibiotics to fight antimicrobial resistance. Plectasin, a small antibiotic, uses an innovative mechanism [...]]]> https://scitechdaily.com/velcro-vs-bacteria-a-new-twist-in-antibiotic-warfare/feed/ 0 https://scitechdaily.com/scientists-uncover-unexpected-hidden-dangers-of-a-common-antibiotic/ https://scitechdaily.com/scientists-uncover-unexpected-hidden-dangers-of-a-common-antibiotic/#comments Sat, 18 May 2024 02:30:38 +0000 https://scitechdaily.com/?p=384063

In emergency rooms and intensive care units nationwide, healthcare professionals must quickly decide on antibiotics for patients suspected of having severe infections. A recent study from the University of Michigan indicates that these rapid decisions could lead to unexpected effects on patient outcomes. Beginning in 2015, a 15-month national shortage of a commonly prescribed antibiotic, [...]]]> https://scitechdaily.com/scientists-uncover-unexpected-hidden-dangers-of-a-common-antibiotic/feed/ 2 https://scitechdaily.com/when-giants-fight-microscopic-wars-jumbo-viruses-tackle-superbugs/ https://scitechdaily.com/when-giants-fight-microscopic-wars-jumbo-viruses-tackle-superbugs/#respond Sun, 12 May 2024 06:30:20 +0000 https://scitechdaily.com/?p=381140

In the early 20th century, antibiotics gained widespread recognition as an effective treatment for bacterial infections. In what is deemed as the antibiotic golden age, they were regularly developed throughout the mid-20th century. However, this golden age did not last. As antibiotics were prescribed more frequently, bacteria evolved. They became better equipped to defeat antibiotics, [...]]]> https://scitechdaily.com/when-giants-fight-microscopic-wars-jumbo-viruses-tackle-superbugs/feed/ 0 https://scitechdaily.com/when-antibiotics-fail-mit-scientists-use-ai-to-target-sleeper-bacteria/ https://scitechdaily.com/when-antibiotics-fail-mit-scientists-use-ai-to-target-sleeper-bacteria/#respond Fri, 03 May 2024 15:55:57 +0000 https://scitechdaily.com/?p=374928

Most antibiotics target metabolically active bacteria, but with artificial intelligence, researchers can efficiently screen compounds that are lethal to dormant microbes. Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats. When an [...]]]> https://scitechdaily.com/when-antibiotics-fail-mit-scientists-use-ai-to-target-sleeper-bacteria/feed/ 0 https://scitechdaily.com/newly-discovered-peptide-could-treat-incurable-bacterial-infections/ https://scitechdaily.com/newly-discovered-peptide-could-treat-incurable-bacterial-infections/#respond Fri, 03 May 2024 05:23:09 +0000 https://scitechdaily.com/?p=380838

A peptide with antimicrobial properties derived from cows shows promise for treating incurable infections from the bacteria commonly found in the intestines. University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such [...]]]> https://scitechdaily.com/newly-discovered-peptide-could-treat-incurable-bacterial-infections/feed/ 0 https://scitechdaily.com/superbug-slayer-new-class-of-antibiotics-proves-potent-against-multi-drug-resistant-bacteria/ https://scitechdaily.com/superbug-slayer-new-class-of-antibiotics-proves-potent-against-multi-drug-resistant-bacteria/#respond Tue, 30 Apr 2024 17:33:10 +0000 https://scitechdaily.com/?p=379699

A new class of antibiotics capable of combating multi-drug resistant bacteria and treating bloodstream infections in mice has been unveiled by Uppsala University scientists. Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic [...]]]> https://scitechdaily.com/superbug-slayer-new-class-of-antibiotics-proves-potent-against-multi-drug-resistant-bacteria/feed/ 0 https://scitechdaily.com/no-antibiotics-needed-revolutionary-chronic-wound-treatment-could-help-millions/ https://scitechdaily.com/no-antibiotics-needed-revolutionary-chronic-wound-treatment-could-help-millions/#respond Sun, 28 Apr 2024 08:30:18 +0000 https://scitechdaily.com/?p=376620

An international team of scientists has developed a new treatment for chronic wounds that uses ionized gas to activate a wound dressing, without the need for antibiotics. The treatment involves the plasma activation of hydrogel dressings (that are commonly used in wound dressings) with a unique mix of different chemical oxidants that are effective in [...]]]> https://scitechdaily.com/no-antibiotics-needed-revolutionary-chronic-wound-treatment-could-help-millions/feed/ 0 https://scitechdaily.com/combating-the-next-pandemic-experts-call-for-global-genetic-warning-system/ https://scitechdaily.com/combating-the-next-pandemic-experts-call-for-global-genetic-warning-system/#respond Thu, 25 Apr 2024 09:00:19 +0000 https://scitechdaily.com/?p=378498

Scientists champion global genomic surveillance using the latest technologies and a ‘One Health’ approach to protect against novel pathogens like avian influenza and antimicrobial resistance, catching epidemics before they start. The COVID-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, [...]]]> https://scitechdaily.com/combating-the-next-pandemic-experts-call-for-global-genetic-warning-system/feed/ 0 https://scitechdaily.com/antibiotic-breakthrough-revolutionary-chinese-study-paves-way-for-superbug-defeating-drugs/ https://scitechdaily.com/antibiotic-breakthrough-revolutionary-chinese-study-paves-way-for-superbug-defeating-drugs/#respond Tue, 23 Apr 2024 21:43:45 +0000 https://scitechdaily.com/?p=374177

New research reveals that fluorous lipopetides act as highly effective antibiotics. Bacterial infections resistant to multiple drugs, which no existing antibiotics can treat, represent a significant worldwide challenge. A research group from China has presented a new strategy for creating innovative antibiotics aimed at combating these resistant bacteria in the journal Angewandte Chemie. This approach [...]]]> https://scitechdaily.com/antibiotic-breakthrough-revolutionary-chinese-study-paves-way-for-superbug-defeating-drugs/feed/ 0 https://scitechdaily.com/scientists-discover-new-antibiotic-class-effective-against-drug-resistant-bacteria/ https://scitechdaily.com/scientists-discover-new-antibiotic-class-effective-against-drug-resistant-bacteria/#respond Mon, 22 Apr 2024 23:15:36 +0000 https://scitechdaily.com/?p=371503

Researchers at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in a study recently published in the journal PNAS. Antibiotics are the foundation of modern medicine and over the last century [...]]]> https://scitechdaily.com/scientists-discover-new-antibiotic-class-effective-against-drug-resistant-bacteria/feed/ 0 https://scitechdaily.com/umbrella-toxins-a-groundbreaking-class-of-antimicrobials-found-in-soil-bacteria/ https://scitechdaily.com/umbrella-toxins-a-groundbreaking-class-of-antimicrobials-found-in-soil-bacteria/#comments Fri, 19 Apr 2024 14:52:10 +0000 https://scitechdaily.com/?p=376687

Umbrella-shaped proteins discovered by scientists target and kill specific bacteria, holding promise for treating resistant infections. Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species. The discovery of the umbrella toxin particles and related information about their structures, composition, [...]]]> https://scitechdaily.com/umbrella-toxins-a-groundbreaking-class-of-antimicrobials-found-in-soil-bacteria/feed/ 1 https://scitechdaily.com/warning-new-research-indicates-that-your-pet-dog-or-cat-could-be-spreading-deadly-superbugs/ https://scitechdaily.com/warning-new-research-indicates-that-your-pet-dog-or-cat-could-be-spreading-deadly-superbugs/#comments Mon, 15 Apr 2024 21:08:32 +0000 https://scitechdaily.com/?p=375291

Pet dogs and cats in Portugal and the UK were found to harbor the same antibiotic-resistant bacteria as their owners. New research to be presented at the ESCMID Global Congress in Barcelona, Spain, from April 27 to April 30, indicates that pet dogs and cats significantly contribute to the spread of antibiotic-resistant bacteria. The study [...]]]> https://scitechdaily.com/warning-new-research-indicates-that-your-pet-dog-or-cat-could-be-spreading-deadly-superbugs/feed/ 5 https://scitechdaily.com/mits-ai-breakthrough-pioneering-new-antibiotics-to-combat-mrsa/ https://scitechdaily.com/mits-ai-breakthrough-pioneering-new-antibiotics-to-combat-mrsa/#respond Thu, 04 Apr 2024 09:32:27 +0000 https://scitechdaily.com/?p=362403

These compounds can kill methicillin-resistant Staphylococcus aureus (MRSA), a bacterium that causes deadly infections. Using a type of artificial intelligence known as deep learning, MIT researchers have discovered a class of compounds that can kill a drug-resistant bacterium that causes more than 10,000 deaths in the United States every year. In a study published recently [...]]]> https://scitechdaily.com/mits-ai-breakthrough-pioneering-new-antibiotics-to-combat-mrsa/feed/ 0