Opioid receptors located in the dorsal peduncular nucleus uniquely contribute to the rewarding effects of…
Browsing: Opioids
Opioids are a class of drugs that include both naturally occurring and synthetic substances derived from the opium poppy, as well as synthetic analogues. They are primarily used for their potent pain-relieving properties, making them essential in the management of moderate to severe pain, especially in settings such as post-operative care or chronic pain conditions. Common examples include morphine, heroin, fentanyl, and codeine. Besides pain relief, opioids can produce feelings of euphoria, which contributes to their potential for misuse and addiction. The use of opioids activates specific receptors in the brain, nervous system, and gastrointestinal tract, leading to effects such as drowsiness, constipation, and, at higher doses, respiratory depression, which can be fatal. Due to their high potential for dependence and overdose, opioids are heavily regulated in many countries, and there is a strong focus on monitoring their prescription and use to combat the opioid crisis that has particularly affected the United States.
Newly identified compound enhances naloxone’s potency and duration, according to a mouse study. The ongoing…
Researchers at Mainz University have discovered a natural compound that could potentially serve as a…
Scientists have developed new biosensors that enable real-time tracking of opioid signaling in the brain,…
Xylazine, a potent animal tranquilizer, has entered the UK drug scene, causing significant health risks…
A UCLA Health study shows that insomnia drug prevents opioid addiction in mice at opioid…
Researchers at the Comprehensive Center for Pain & Addiction conducted tests on five terpenes, finding…
Chemical biologists at Scripps Research have developed a preliminary “proof-of-concept” vaccine, potentially paving the way…
NIH-supported study highlights increasingly dangerous illicit drug supply, risk of pills not coming from a…
U.S. fentanyl seizures skyrocketed by over 1,700% from 2017 to 2023, with nearly half of…
The testing method has the capability to examine blood samples in half the time compared…
The first-of-its-kind electrochemical test can identify trace quantities with a 98% accuracy rate. Researchers at…
Our understanding of the role of opioid medicines in cancer pain is challenged by a…
Letters notifying physicians of patient overdose deaths and providing a plan for the future is…
A study from Rutgers suggests that enhancing prison reentry programs could reduce the opioid overdose…
A new study led by Brown University researchers suggests a need to reevaluate opioid addiction…
According to the Centers for Disease Control, overdoses claim the lives of 100,000 Americans annually,…
NIH-funded study suggests the need to reevaluate opioid addiction treatment recommendations in the era of…